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Adam Knepp, Biomedical Fellow
RU Graduate Program
Laboratory of Molecular Biology and Biochemistry
Rockefeller Research Building 510
The Rockefeller University, Box 187
1230 York Avenue
New York, NY 10065
Telephone: 212-327-8284
Fax: 212-327-7904 aknepp@rockefeller.edu
 Biosketch
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Education:
Graduate Fellow, Rockefeller University, September 2008 – present
B.S. in Chemistry, Stanford University, 2008
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Research:
Single Molecule Analysis of Chemokine Receptor Complexes
Nature has evolved a remarkably complex signaling network of chemokines and chemokine receptors in order to coordinate the recruitment and activation of immune cells necessary for response. In addition to their normal physiological functions, these complexes are of great interest for their roles in a number of pathologies, including autoimmune disorders, pulmonary diseases, cancer, vascular diseases, and HIV. I am interested in developing chemical and biophysical tools to study the structural dynamics of these important proteins at a single molecule level. Information on how these complexes assemble and disassemble would greatly assist ongoing therapeutic efforts.
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Awards:
Honorable Mention, National Science Foundation Graduate Research Fellowship, 2009
Graduated from Stanford University with Distinction, 2008
VPUE Summer Research Grant, Stanford University, 2007
Physical Sciences Institute, Sandia National Laboratories, 2005-2006
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Published Papers:
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2).
Ismail, H; Abel, PR; Green, WH; Fahr, A; Jusinski, LE; Knepp, AM; Zador, J; Meloni, G; Selby, TM; Osborn, DL; Taatjes, CA
Temperature-dependent kinetics of the vinyl radical (C2H3) self-reaction
J. Phys. Chem. A, 113, 1278-1286 (2009).
PMID: 19146471 [PubMed]
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1).
Knepp, AM; Meloni, G; Jusinski, LE; Taatjes, CA; Cavalotti, C; Klippenstein, SJ
Theory, measurements, and modeling of OH and HO2 Formation in the reaction of cyclohexyl radicals with O2
Phys. Chem. Chem. Phys., 9, 4315-4331 (2007).
PMID: 17687479 [PubMed - indexed for MEDLINE]
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Posters:
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3).
Hall, E.; Kim, S.; Knepp, A.M.
"A Microfluidic Platform for the Culture & Analysis of Single Cells."
2008 Biophysical Society Meeting.
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2).
Knepp, A. M.; Meloni, G.; Jusinski, L. E.; Taatjes, C. A.
“Measurements of Product Formation in the Reaction of Cyclohexyl Radicals with O2.”
2007 Western Spectroscopy Association Conference.
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1).
Jusinski, L. E.; Knepp, A. M.; Taatjes, C. A.
“Measurements of the Rate Constant of the Vinyl Radical Self-Reaction Between 298 and 600 K.”
2005 International Conference of Chemical Kinetics.
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Education | Research | Awards | Published Papers | Posters