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116).
Ludeke, S., Beck, M., Yan, E. C., Sakmar, T. P., Siebert, F. & Vogel, R.
The Role of Glu181 in the Photoactivation of Rhodopsin.
J Mol Biol 353:345–356 (2005).
PMID: 16169009 [PubMed - indexed for MEDLINE]
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114).
Sakmar, T. P.
Twenty Years of the Magnificent Seven.
The Scientist 19:22-23 (2005). [*Cover Article]
[not indexed for MEDLINE]
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112).
Yan, E. C., Ganim, Z., Kazmi, M. A., Chang, B. S. W., Sakmar, T. P. & Mathies, R. A.
Resonance Raman Analysis of the Mechanism of Energy Storage and Chromophore Distortion in the Primary Visual Photoproduct.
Biochemistry 43:10867–10876 (2004).
PMID: 15323547 [PubMed - indexed for MEDLINE]
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111).
Lewis, J. W., Szundi, I., Kazmi, M. A., Sakmar, T. P. & Kliger, D. S.
Time-Resolved Photointermediate Changes in Rhodopsin Glu181 Mutants.
Biochemistry 43:12614–12621 (2004).
PMID: 15449951 [PubMed - indexed for MEDLINE]
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110).
Billick, E., Seibert, C., Pugach, P., Ketas, T., Trkola, A., Endres, M. J., Murgolo, N. J., Coates, E., Reyes, G. R., Baroudy, B. M., Sakmar, T. P., Moore, J. P. & Kuhmann, S. E.
The Differential Sensitivity of Human and Rhesus Macaque CCR5 to Small-Molecule Inhibitors of Human Immunodeficiency Virus Type 1 Entry Is Explained by a Single Amino Acid Difference and Suggests a Mechanism of Action for These Inhibitors.
J Virol 78:4134–4144 (2004).
PMID: 15047829 [PubMed - indexed for MEDLINE]
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106).
Yan, E. C., Kazmi, M. A., Ganim, Z., Hou, J. M., Pan, D., Chang, B. S. W., Sakmar, T. P. & Mathies, R. A.
Retinal Counterion Switch in the Photoactivation of the G Protein-Coupled Receptor Rhodopsin.
Proc Natl Acad Sci U S A 100:9262–9267 (2003).
[*See commentary: Birge, R. R. & Knox, B. E. Perspectives on the Counterion Switch-Induced Photoactivation of the G Protein-Coupled Receptor Rhodopsin. Proc Natl Acad Sci U S A 100:9105–9107 (2003).]
PMID: 12835420 [PubMed - indexed for MEDLINE]
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105).
Tsamis, F., Gavrilov, S., Kajumo, F., Seibert, C., Kuhmann, S., Ketas, T., Trkola, A., Palani, A., Clader, J. W., Tagat, J. R., McCombie, S., Baroudy,B., Moore, J. P., Sakmar, T. P. & Dragic, T.
Analysis of the Mechanism by Which the Small-Molecule CCR5 Antagonists SCH-351125 and SCH-350581 Inhibit Human Immunodeficiency Virus Type 1 Entry.
J Virol 77:5201–5208 (2003).
PMID: 12692222 [PubMed - indexed for MEDLINE]
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103).
Seibert, C., Cadene, M., Sanfiz, A., Chait, B. T. & Sakmar, T. P.
Tyrosine Sulfation of CCR5 N-Terminal Peptide by Tyrosylprotein Sulfotransferases 1 and 2 Follows a Discrete Pattern and Temporal Sequence.
Proc Natl Acad Sci U S A 99:11031–11036 (2002).
PMID: 12169668 [PubMed - indexed for MEDLINE]
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102).
Unson, C. G., Wu, C. –R., Yoo, B., Cheung, C., Jiang, Y., Sakmar, T. P. & Merrifield, R. B.
The Roles of Specific Extracellular Domains of the Glucagon Receptor in Ligand Binding and Signaling.
Biochemistry 41:11795–11803 (2002).
PMID: 12269822 [PubMed - indexed for MEDLINE]
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101).
De, S. & Sakmar, T. P.
Interaction of A2E with Model Membranes. Implications to the Pathogenesis of Age-Related Macular Degeneration.
J Gen Physiol 120:147–157 (2002).
PMID: 12149277 [PubMed - indexed for MEDLINE]
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100).
Gopala Krishna, A., Menon, S. T., Terry, T. J.& Sakmar, T. P.
Evidence That Helix 8 of Rhodopsin Acts As a Membrane-Dependent Conformational Switch.
Biochemistry 41:8298–8309 (2002).
PMID: 12081478 [PubMed - indexed for MEDLINE]
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99).
Chang, B. S. W., Jönsson, K., Kazmi, M. A., Donoghue, M. J. & Sakmar, T. P.
Recreating a Functional Ancestral Archosaur Visual Pigment.
Mol Biol Evol 19:1483–1489 (2002). [*Rated “EXCEPTIONAL” by the Faculty of 1000]
PMID: 12200476 [PubMed - indexed for MEDLINE]
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98).
Marin, E. P., Gopala Krishna, A. & Sakmar, T. P.
Disruption of the a5 Helix of Transducin Impairs Rhodopsin-Catalyzed Nucleotide Exchange.
Biochemistry 41:6988–6994 (2002).
PMID: 12033931 [PubMed - indexed for MEDLINE]
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97).
Yan, E. C., Kazmi, M. A., De, S., Chang, B. S. W., Seibert, C., Marin, E. P., Mathies, R. A. & Sakmar, T. P.
Function of Extracellular Loop 2 in Rhodopsin: Glutamic Acid 181 Modulates Stability and Absorption Wavelength of Metarhodopsin II.
Biochemistry 41:3620–3627 (2002).
PMID: 11888278 [PubMed - indexed for MEDLINE]
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96).
Sakmar, T. P.
The Structure of Rhodopsin and the Superfamily of Seven-Helical Receptors: The Same and Not the Same.
Curr Opin Cell Biol 14:189–195 (2002).
PMID: 11891118 [PubMed - indexed for MEDLINE]
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94).
Chang, B. S. W., Kazmi, M. & Sakmar, T. P.
Synthetic Gene Technology: Applications to Ancestral Gene Reconstruction and Structure-Function Studies of Receptors.
Methods Enzymol 343:274–294 (2002).
PMID: 11665573 [PubMed - indexed for MEDLINE]
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93).
Jiang, Y., Cypess, A. M., Muse, E. D., Wu, C-. R., Unson, C. G., Merrifield, R. B. & Sakmar, T. P.
Glucagon Receptor Activates Extracellular Signal-Regulated Protein Kinase (ERK) 1/2 via cAMP-Dependent Protein Kinase.
Proc Natl Acad Sci U S A 98:10102–10107 (2001).
PMID: 11517300 [PubMed - indexed for MEDLINE]
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92).
Menon, S. T., Han, M. & Sakmar, T. P.
Rhodopsin: Structural Basis of Molecular Physiology.
Physiol Revs 81:1659–1688 (2001). [*Cover Article]
PMID: 11581499 [PubMed - indexed for MEDLINE]
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91).
Marin, E. P., Krishna, A. G. & Sakmar, T. P.
Rapid Activation of Transducin by Mutations Distant From the Nucleotide-Binding Site: Evidence for a Mechanistic Model of Receptor-Catalyzed Nucleotide Exchange by G Proteins.
J Biol Chem 276:27400–27405 (2001).
PMID: 11356823 [PubMed - indexed for MEDLINE]
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90).
Marin, E. P., Krishna, A. G., Archambault, V., Simuni, E., Fu, W. Y. & Sakmar, T. P.
The Function of Interdomain Interactions in Controlling Nucleotide Exchange Rates in Transducin.
J Biol Chem 276:23873–23880 (2001).
PMID: 11290746 [PubMed - indexed for MEDLINE]
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